New Pathway Discovery Reveals Major Cause of IBD Affecting 1 in 10 in the UK – What You Need to Know

IBD affects 1 in 10 in the UK, but a new pathway discovery could change everything.

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Scientists reveal an 'enhancer' gene in macrophages linked to IBD inflammation.

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ETS2 gene activity in resting macrophages transforms them into inflammatory cells.

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95% of IBD patients carry variants of the ETS2 enhancer, crucial for infection defense.

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MEK inhibitors, existing drugs, show promise in reducing IBD-related inflammation.

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Research collaboration aims to deliver MEK inhibitors directly to macrophages safely.

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The ETS2 pathway is a major cause of IBD, impacting millions globally.

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Young people with IBD face severe symptoms affecting education, relationships, and work.

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Unveiling a new genetic target offers hope for better IBD treatments in the future.

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