Colossal's 'Woolly Mice' Bring Mammoth Revival Closer

Govind Tekale

Scientists at Colossal Biosciences have created genetically modified "woolly mice" with thick, wavy golden coats as part of their mission to resurrect the extinct woolly mammoth.

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The experiment modified seven genes in lab mice targeting traits like hair length, texture, and fat metabolism to mimic mammoth characteristics that once enabled survival in frigid environments.

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Colossal aims to produce mammoth-like Asian elephant embryos by 2026 and their first calves by 2028, while also pursuing de-extinction of the dodo bird and Tasmanian tiger.

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Using CRISPR technology, researchers compared ancient mammoth DNA with elephant sequences, though the resulting mice showed longer fur but no apparent increase in fat reserves.

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Scientific reception has been mixed, with some experts impressed by the genetic achievement while others point out similar "fancy mice" with comparable hair traits have existed since the 1800s.

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Critics warn of potential ecological disruption, with one scientist questioning: "I don't know what the downside of having a bunch of hairy Asian elephants stomping around in the tundra might be."

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Defenders argue de-extinction technologies could benefit threatened ecosystems, though skeptics maintain resources would be better directed toward saving currently endangered species.

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Geneticist Adam Rutherford called mammoth de-extinction "scientific folly" and "morally questionable" given the 6-million-year evolutionary gap between mammoths and Asian elephants—similar to humans and chimpanzees.

Photo Source: Nikhil Nuance nation (Pexels)