UW researchers, utilizing post-mortem brain samples from 22 ADRC project participants, have unearthed pivotal insights on human microglia and their intricate relationship with Alzheimer’s disease. Microglia, vividly depicted in green, adopt a reactive shape when associated with amyloid-β deposits, showcased in purple. Alternatively, they assume a homeostatic shape in the parenchyma, distant from Aβ. Serving as the brain’s immune system, microglia’s primary role is paramount. These cells undertake a multitude of tasks, with one of the most significant being the digestion of abnormal protein clumps intrinsically linked to Alzheimer’s disease. Emerging evidence suggests that certain microglia cells might exhibit an … Continue reading The Brain’s Unsung Heroes: How Microglia Cells are Shaping Alzheimer’s Research!