Spermidine Supplement Recall: Dorado Nutrition’s 120-Capsule Bottles Pulled for Undeclared Wheat

A popular supplement has been pulled from online shelves due to a potentially dangerous unlisted ingredient. On April 16, 2025, Supplement Manufacturing Partner, Inc. launched a recall of Dorado Nutrition brand Spermidine Maximum Strength 10mg vegetable capsules after tests revealed the presence of wheat that wasn’t declared on the product label.

For the thousands of Americans with wheat allergies, this oversight isn’t just an inconvenience—it could trigger severe or even life-threatening allergic reactions.

The recalled supplements were sold on Amazon between May 22, 2024, and April 4, 2025. The same product was also distributed in Germany under the name “Spermidin 60 Kapseln 38g” by Deep Green GmbH, also known as Space Garden.

How to identify the recalled product

If you’ve purchased this supplement, check for these specific details:

• White bottle containing 120 vegetable capsules
• Blue outlined label
• Best By Date: 04/2026 (located on the bottom of the bottle)
• Lot Numbers: 12792402-44 and 12792402-44J

While no allergic reactions have been reported so far, the company is urging consumers to return the product to the place of purchase for a full refund. Questions can be directed to [email protected] or by phone at 833-810-9896 between 9 AM and 5 PM EST.

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The danger of undeclared wheat

Wheat allergies might not be as common as peanut or shellfish allergies, but they can be equally dangerous. Symptoms range from mild skin reactions like hives and itching to more serious issues including difficulty breathing, swelling of the throat, and potentially life-threatening anaphylaxis.

Unlike celiac disease or wheat intolerance, true wheat allergies involve the immune system’s immediate and sometimes severe response to wheat proteins. For affected individuals, even trace amounts can trigger reactions, making accurate product labeling vital.

The Food Allergen Labeling and Consumer Protection Act requires clear identification of major allergens including wheat on all food and supplement labels—a requirement that wasn’t met in this case.

What is spermidine anyway?

For those unfamiliar with the recalled product, spermidine is a naturally occurring compound that has gained popularity in the supplement market due to growing research into its potential health benefits.

It’s being studied for its role in a cellular process called autophagy—essentially the body’s way of cleaning out damaged cells to regenerate newer, healthier cells. Some research suggests it might have benefits for heart health, brain function, and possibly even longevity, though many of these studies are still in early stages.

For those interested in spermidine but concerned about supplements, it’s naturally found in foods like aged cheese, mushrooms, whole grains, soybeans, and legumes.

The bigger picture on supplement safety

This recall highlights a common issue in the supplement industry. Unlike prescription medications, dietary supplements don’t require FDA approval before hitting the market. The responsibility for ensuring safety and proper labeling falls primarily on manufacturers.

The FDA typically takes action only after problems are discovered, as happened with this recall. Common reasons for supplement recalls include undeclared allergens, contamination with bacteria or heavy metals, incorrect dosages, or inclusion of ingredients not listed on the label.

The case serves as a reminder for consumers—especially those with allergies—to research manufacturers and be aware of the limited pre-market oversight in the supplement industry.

Anyone who has used this product and experienced symptoms consistent with an allergic reaction should consult a healthcare provider, even if the symptoms seemed mild at the time.