LOY-002: FDA-Approved Drug May Extend Senior Dogs' Lives by 1 Year

[{"selector":"#anim-76290bc6-ea4d-4d5a-821d-33eb0a9d108a","keyframes":{"opacity":[0,1]},"delay":500,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fdcb5936-0cd1-4349-a213-b2f293fd323c","keyframes":{"transform":["translate3d(-116.609%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d79f45c3-06be-48aa-ae6f-317137d4ca6b","keyframes":{"opacity":[0,1]},"delay":800,"duration":500,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2b038068-3075-4933-872a-20bf3221f3c5","keyframes":{"transform":["translate3d(-122.3301%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":800,"duration":500,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] LOY-002: FDA-Approved Drug May Extend Senior Dogs' Lives by 1 Year Govind Tekale

Biotech firm Loyal has developed LOY-002, a drug that mimics caloric restriction benefits to potentially extend dogs' lifespans.

[{"selector":"#anim-76c4d56b-ed68-470e-a7ae-b51bb3fd341f","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-90cead27-5f9c-4159-b02c-06ee5f213483","keyframes":{"transform":["translate3d(115.50632%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bb70a527-ca15-45d1-86fd-883f6f0f7a56","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f0631475-77bd-465e-a36e-8b44c701f6ab","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-81fb8648-b557-425f-a418-a91a2f1e4b7d","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Generative Medicine Foundation (CC BY-NC 3.0 US)

The FDA's Center for Veterinary Medicine has already accepted the "Reasonable Expectation of Effectiveness" portion of the approval process.

[{"selector":"#anim-8783ffaf-194b-4262-9e79-6712bc5a6639","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5bb0b4df-cdbd-4d3b-a581-4203e4deb8a9","keyframes":{"transform":["translate3d(0px, 162.72400%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-80925389-4241-4a07-8755-1de3d408c526","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-319d2ffd-9e4e-4bc6-951e-ad63f1afe89a","keyframes":{"transform":["translate3d(0px, -111.1955%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e251e949-949a-44da-824b-6042a8b8ae55","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] ON POINT LEGAL LEADS (CC BY-NC 4.0)

Large breeds like Great Danes typically live just 6-8 years, while small breeds can reach 12-20 years – a gap this drug aims to narrow.

[{"selector":"#anim-216d593e-b006-4004-ab4e-3e817c668d51","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3758f86e-cee9-4f26-9cb2-3a76a4763edc","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c5b0c848-7686-43f9-9cbd-36f013cc07b9","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0ae8efc9-dbdd-4271-809d-ba24b2289a05","keyframes":{"transform":["translate3d(113.60759%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d2e0c535-2fa2-481d-a636-9f52b8c0d16c","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Flickr (CC BY 2.0)

Loyal's STAY study, involving over 1,000 senior dogs across U.S. clinics, represents the largest veterinary clinical trial in history.

[{"selector":"#anim-0ae42398-918d-4527-9a4c-f35f87cad061","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-31dda397-f4e0-4cd3-8039-2c69c1c34879","keyframes":{"transform":["translate3d(0px, 193.19549%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d9fd1b1e-90e9-471b-b837-ba79092d833e","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-92b49df7-9df1-412e-8004-c426d1f88d8a","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-729072bd-d804-4cfc-9bc7-9e37e0a06d9f","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Pexels

Researchers track improvements in energy levels, brain function, and mobility – not just how long dogs live but how well they age.

[{"selector":"#anim-c2326b7f-b818-4f3c-b480-119b5ce089ef","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f31fded4-13bc-44e2-b2d6-cfc8ce86dbad","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-60c7fad1-8964-43a3-a18a-87960da75616","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ea956462-9ec6-4fab-b271-a5bf0a2bee7d","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-51c39de4-596f-4de6-9a05-6c625ee3d202","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Stock cake (CC0 1.0)

CEO Celine Halioua emphasizes their goal extends beyond longevity to enhancing quality of life for senior dogs.

[{"selector":"#anim-62905fb0-64e5-45c9-a458-015233d9c8f6","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-63e07fb7-579a-43c3-8310-127e80e05bc5","keyframes":{"transform":["translate3d(0px, 244.87591%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-95aab0be-3f73-40e2-bbd0-4b4d97605270","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ec0a986c-b6d9-4d8c-9aa4-c1998b5cc549","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0f1bfab6-1539-49be-81b8-3a24fff8a364","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: The collar club academy (CC BY-NC 4.0)

Dogs share many age-related health problems with humans, making them excellent subjects for aging research.

[{"selector":"#anim-2cce8915-ad3c-4b52-b8b6-1b4ff4a87485","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f7fa210e-1ca8-476e-a8f2-514aa3c87351","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ea26710a-4c59-4f92-8a52-e7478ca992fa","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-78e08706-945c-4c0f-978c-a14cb965bf3b","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5266f465-f1d3-4283-a062-c06618eec6af","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Flickr (CC BY-NC-SA 2.0)

Success with canine longevity drugs could accelerate similar treatments for humans, as dogs age faster but live in identical environments.

[{"selector":"#anim-9dd5f228-fd4a-4e91-84a0-ff215a26d508","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f3f02713-6a52-4eed-ba63-051bdd3d40cb","keyframes":{"transform":["translate3d(0px, 196.29626%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9dac8e07-e6e7-48c0-8f80-18ce28318627","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e04b1734-2201-4126-b11c-08ad6cc4499e","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-96f7bbe2-30d0-4285-9351-5db3365aa141","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Stock Cake (CC0 1.0)

Loyal has secured $22 million in recent funding, signaling strong investor confidence in the growing pet healthcare technology sector.

[{"selector":"#anim-dee11fd1-3b06-4bf7-91a1-d524cfa703e6","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c3395423-f569-44e9-8e72-171d4ae77e1a","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5561e832-29a5-49d5-9bbe-cae8508d2d06","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9ca878aa-f37e-401c-a09a-665c4b551538","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2aa995da-434d-4d79-be04-ba5363ecd27d","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Flickr (CC BY-NC-ND 2.0)

[{"selector":"#anim-b6014985-6e39-4992-a86c-2e6cc40d4f43","keyframes":{"opacity":[0,1]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3a0748a5-f570-4581-b627-c96735ad2bda","keyframes":{"opacity":[0,1]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b88e750b-e185-4d56-9eb0-aaf7f7b88d37","keyframes":{"transform":["translate3d(-114.50152%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ae17bec4-3408-45e2-bf7c-feb80385fc59","keyframes":{"opacity":[0,1]},"delay":700,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7d7ede60-4765-40d2-886f-26e96663b8db","keyframes":{"transform":["translate3d(115.23810%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":700,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Bonobo Kanzi: 44, Language Pioneer, Toolmaker, Dies Suddenly Learn more