The United States has reported its first outbreak of H7N9 bird flu since 2017, affecting a commercial chicken flock in Mississippi. This development comes as health officials already grapple with the H5N1 strain that has infected dairy cows and one human in the U.S.
Key Details
The outbreak occurred on a Mississippi poultry farm with 47,654 commercial broiler breeder chickens, according to the World Animal Health Organisation. Officials have begun depopulating the affected flock to prevent further spread.
“Highly pathogenic avian influenza (HPAI) H7N9 of North American wild bird lineage was detected in a commercial broiler breeder chicken flock in Mississippi. Depopulation of the affected flock is in progress,” states the official report.
The USDA’s Animal and Plant Health Inspection Service (APHIS) and state health officials are conducting epidemiological investigations and enhanced surveillance in response to the detection.
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H7N9 vs. H5N1: Understanding the Threat
While H5N1 has caused widespread damage to poultry flocks recently, the H7N9 strain presents a potentially greater human health risk. According to the World Health Organisation, H7N9 has killed nearly 40% of infected humans since its discovery in 2013.
This high mortality rate makes the current outbreak particularly concerning for public health experts watching for potential pandemic threats.
Global Context
Bird flu outbreaks have forced the culling of hundreds of millions of poultry globally, disrupting supply chains and contributing to higher food prices. The recent spread to mammals, including dairy cows in the U.S., has heightened concerns about the virus’s potential to mutate and pose a greater risk to humans.
The current situation requires careful monitoring, particularly since both major strains (H5N1 and now H7N9) are active in the United States simultaneously.

Pandemic Concerns
The virus’s ability to spread to mammals raises concerns about its pandemic potential. Experts particularly worry about genetic reassortment—when different flu strains exchange genetic material—which could increase transmissibility between humans.
While human-to-human transmission of H7N9 remains rare, health authorities emphasize the need for continued vigilance and preventive measures, especially among those who work closely with poultry or in food production.
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