Common Drug Could Reduce COVID-19 Risk

[{"selector":"#anim-3be68088-fbfa-435b-8bfb-016abb5dd11e","keyframes":{"opacity":[0,1]},"delay":500,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2759a9b1-2514-4d9f-8864-ed9c3f8d24ee","keyframes":{"transform":["translate3d(-117.08861%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":500,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5f4d1093-1ea4-4ca6-965e-118d64c3934a","keyframes":{"opacity":[0,1]},"delay":800,"duration":500,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-14ce4817-7390-459e-a95e-bfa846d65b41","keyframes":{"transform":["translate3d(-126.2136%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":800,"duration":500,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Common Drug Could Reduce COVID-19 Risk Tejal Somvanshi

Bone-strengthening drugs linked to lower COVID-19 rates, as Harvard study of 450,000 patients shows reduced infection, diagnosis, and hospitalization.

[{"selector":"#anim-14a14c5a-0d1d-4867-a2ef-3b505f0f8b9c","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-92ae2136-bd74-4573-8807-843112651dac","keyframes":{"transform":["translate3d(115.50632%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3c69978d-332e-435c-be21-06becdbb8dc1","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-084f6237-be5a-4e8f-b551-b58b87e99689","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8fb16b85-26c7-4568-aeb7-c8535bd3c75d","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Towfiqu barbhuiya (Pexels)

University of York scientists explain how bisphosphonates like alendronate and zoledronate may protect against COVID-19.

[{"selector":"#anim-0855c036-b368-4e36-a270-396c4b55b4db","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1ef730c7-ff71-487a-baa5-a36592735db4","keyframes":{"transform":["translate3d(0px, 197.04866%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4975c667-441f-4e5e-a772-ce33266616dd","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cfcfbd02-6bc3-4301-b938-6127f894de65","keyframes":{"transform":["translate3d(0px, -113.72714%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-748fdb69-e67b-4092-a02f-30730c77fec7","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Chokniti Khongchum (Pexels)

Bisphosphonates bind to specific enzyme domains found in nidoviruses, including coronaviruses, which may inhibit viral replication.

[{"selector":"#anim-f6c77a0c-2a17-4d47-8331-f139a2fc0544","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-14b4c48e-4373-424c-8f79-3a008651f3d0","keyframes":{"transform":["translate3d(0px, 116.58885%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-101f5e2b-5795-4fdc-bb12-e4732999035d","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6f015b03-d750-4ec1-af84-185dd0795422","keyframes":{"transform":["translate3d(113.60759%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0b6b87e0-bc15-4694-8a2e-d715f503bda6","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Polina Tankilevitch (Pexels)

Researchers analyzed 7,817 existing drugs, narrowing down to 214 promising candidates in their search for COVID-19 treatments.

[{"selector":"#anim-2a74662d-c0f4-49db-bd53-063e9b03478e","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c8fe43af-6729-4a63-9339-cf48099b59ea","keyframes":{"transform":["translate3d(0px, 197.04866%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-951784a8-6b2f-40f1-b7d5-88a46ef56c02","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5f0040bb-44ea-4761-b837-f7f9f871dfb8","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-79fe82fe-fcee-43fc-a34f-ac54690cf802","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Ishaan Aggarwal (Pexels)

From screening 1,992 bisphosphonates, three drugs emerged as promising candidates: alendronate, zoledronate, and Japan's minodronate.

[{"selector":"#anim-06dc1255-d8b7-4cc8-b9dc-17afd1e42bc0","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-93673a18-1cbf-4108-9dd6-6d3c5c34f429","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e4b67c2d-dd85-42e7-bc02-5b886ed91bf7","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3614249f-e693-4b61-b9c5-330997e72d04","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1236985d-51ec-477d-b9cb-d6e31c9ea92b","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Mart Production(Pexels)

Current COVID-19 vaccines cannot prevent virus transmission, pushing scientists to find new treatments against mutating variants.

[{"selector":"#anim-fa3aec34-ce68-48e6-8676-680844e079f2","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e34a4b15-1679-45d2-93a3-61d5509cc4fd","keyframes":{"transform":["translate3d(0px, 162.72400%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ae2799c7-155f-4aba-931d-e5630ea9a81e","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-41f5221a-f7a4-4600-834f-d23632f835bb","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-dfe2bc01-7e38-497f-8b9f-d8aa731a65bb","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Frank Merino (Pexels)

Professor Seshadri Vasan's team created a specialized database in 2023 to help scientists narrow their search for COVID-19 fighting drugs.

[{"selector":"#anim-9c3d6f4b-f769-4f39-bf09-11e7c7244899","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-92c5eae7-9f66-4f9b-b2e9-a05513d74f11","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-71af76a1-85bb-4ed2-88f1-16eb89ba003d","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fe8d9703-904b-4c39-b489-41a459851b52","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9204225e-ab83-4120-b990-638364183b6b","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Alena Shekhovtcova (Pexels)

These approved osteoporosis medications represent a potential approach of using existing drugs for COVID-19 treatment.

[{"selector":"#anim-2cf3e567-7c82-4801-9760-1e6cc9ccfe11","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-43cea450-37ce-4e10-81e3-4922193ff62c","keyframes":{"transform":["translate3d(0px, 197.82990%, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-63c13605-8193-4a0d-bcf7-f307a002f3fa","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b9679165-9eb1-4d84-b08b-8caa63aa8028","keyframes":{"transform":["translate3d(0px, -114.48664%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-abc29d32-a0ed-4388-a50b-274e174ef9cc","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Maksim Goncharenok (Pexels)

Scientists now plan clinical trials to explore these bone-strengthening drugs' potential against COVID-19 and other coronaviruses.

[{"selector":"#anim-5a9a285d-d96b-49aa-915a-943e230e1d21","keyframes":{"opacity":[0,1]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-08a6540e-c0f8-45ee-8e8c-860649e3a209","keyframes":{"transform":["translate3d(0px, 116.02864%, 0)","translate3d(0px, 0px, 0)"]},"delay":400,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c6fe3c2e-f769-4553-917e-e8173c1cb436","keyframes":{"opacity":[0,1]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-039a3691-68e4-4029-93bf-76519ea1dc95","keyframes":{"transform":["translate3d(115.18987%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":300,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0a8e992d-079e-40e5-8b4a-7da23befc051","keyframes":{"opacity":[0,1]},"delay":1400,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Photo Source: Miguel Á. Padriñán (Pexels)

[{"selector":"#anim-423d864e-d11d-402c-b14b-8668b7db9bd4","keyframes":{"opacity":[0,1]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fb6ea644-5be0-4374-be8f-cc5d18d6356b","keyframes":{"opacity":[0,1]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fdba5ac6-6181-4d7b-8293-8730a9259737","keyframes":{"transform":["translate3d(-114.50152%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":200,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3cafa1cd-0a89-4c05-8b36-eea2105ac2e8","keyframes":{"opacity":[0,1]},"delay":700,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6acd9f4f-c014-48fc-a06c-95f91adbeee2","keyframes":{"transform":["translate3d(115.23810%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":700,"duration":3000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] RSV Vaccine Cuts Infant Cases by 77% Amid Rising Elderly Cases Learn more