Paper-Based Sweat Sensor: A Non-Invasive Glucose Monitoring Breakthrough

Tejal Somvanshi

Binghamton University researchers created paper-based biosensors using bacterial spores to monitor glucose through sweat analysis

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Unlike traditional finger-stick blood tests, this innovative system harnesses Bacillus subtilis spores reacting to glucose in potassium-rich fluids.

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Professor Seokheun Choi's team discovered spore-based systems outlast enzyme-based sensors, eliminating refrigeration needs.

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Varying potassium concentrations in individual sweat samples emerge as primary challenge for accurate glucose measurements.

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National Science Foundation backed this research through two grants at Bioelectronics and Microsystems Lab.

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PhD student Yang "Lexi" Gao contributed with background in marine chemistry and paper-based lead ion detection experience.

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The paper-based design developed by researchers proved clean, sustainable, and disposable.

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Research team acknowledges current limitations including lower sensitivity compared to enzymatic biosensors.

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Continued development focuses on refining detection process while maintaining paper-based functionality.

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