Stanford’s Skin Cream Tetanus Vaccine Saves Mice

Tejal Somvanshi

Scientists at Stanford created a cream-based tetanus vaccination that is applied topically

Photo Source: Yan Krukau (Pexels)

Staphylococcus epidermidis, a common skin bacteria that has been altered to exhibit tetanus toxins, is used in the vaccine

Photo source:  Dr. Sahay, CC BY-SA  3.0

The bacterium's surface Aap protein was found to be essential for inducing an immune response

Photo source: NIAID, CC BY 2.0

By encouraging the production of antibodies, the cream may be able to do away with the requirement for injections

Photo Source: Tokenzero, CC BY-SA 4.0

Antibody levels against S. epidermidis in human blood tests were similar to those found in conventional vaccinations

Photo source: PAHO, CC BY-ND 2.0

Trials on mice showed that they could survive even after being exposed to fatal tetanus dosages

Photo source:  Rama, CC BY-SA 2.0 FR

The method may be effective against bacteria, fungus, viruses, and parasites with a single cell

Photo source: CNX OpenStax, CC BY 4.0

In contrast to conventional vaccinations, it might prevent respiratory germs from entering the body through the nose

Photo source: NIAID, CC BY 2.0

Cost-effectiveness, safety issues, and regulatory barriers continue to be obstacles to general access

Photo source: Patrick Boulen, CC BY-NC-ND 2.0